Faculty Interest Inventory
Office for Research
Thu, 2010-09-30 10:55 — ROOTJ2
Center for Biotechnology and Interdisciplinary Studies (CBIS)
Center for Modeling, Simulation and Imaging in Medicine (CEMSIM)
Dr Kotha obtained his undergraduate training in Mechanical Engineering from Regional Engineering College, Tiruchirappalli (now NIT, Trichy) and his Ph.D. in Biomedical engineering from Rutgers University and University of Medicine and Dentistry of New Jersey. He served as a post-doctoral researcher in Aerospace and Mechanical Engineering at the University of Notre Dame and in Orthopaedic Surgery at Washington University in St Louis. Dr Kotha served as faculty at the dental school of the University of Missouri-Kansas City and in Mechanical Engineering at the University of Connecticut prior to joining Rensselaer Polytechnic Institute. Dr Kotha has worked on the experimental and theoretical aspects of bone tissue damage, adaptation and repair, as well as the development of novel materials that can be used to support implants.
Dr Kotha’s research interests lie broadly in the area of developing novel multi-functional materials and devices to understand and control cell/ tissue function. His research areas include cell and tissue mechanics, multi-functional materials, and the development of minimally invasive modalities for imaging and treatment.
For example, in the area of bone biomechanics, Dr Kotha’s group studies the role of mechanical loading on damage and repair to bone at multiple length scales. They characterize how mineral and organic in bone support its deformation as load is applied. When this is combined with novel non-invasive ultrasound based technologies being developed, the overall goal is to make devices that can be used to monitor the risk of bone failure at specific sites. They also evaluate how cells sense deformation of bone and what molecular pathways are activated in response to loading. These studies can be used to develop therapeutics that can be used to create new bone at sites where it is required. In summary, his research on bone will enable the development of novel devices that can enhance new bone formation at specific sites while assaying its fracture risk.
Ph.D., Rutgers University, 2000
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