George I. Makhatadze

George I. Makhatadze
Name: George I. Makhatadze
Title:Constellation Chair
Department Biological Sciences Chemistry and Chemical Biology
School Science
Center Center for Biotechnology and Interdisciplinary Studies (CBIS)
Constellation Biocomputation & Bioinformatics
Bio Dr. Makhatadze completed his postdoctoral work at the Department of Biology at the Johns Hopkins University before moving to his first faculty position in the Department of Chemistry and Biochemistry at Texas Tech University. After three years at Texas Tech he moved to the Penn State University College of Medicine, where he was Professor at the Department of Biochemistry and Molecular Biology and directed a graduate program in Chemical Biology. Dr. Makhatadze joined Rensselaer in 2007 as a Constellation Professor in Biocomputation and Bioinformatics.

Dr. Makhatadze is on the editorial boards of the Journal of Biological Chemistry, Biochemica et Biophysica Acta, and Protein Engineering, Design and Selection. He is a member of the American Chemical Society, the American Society for Biochemistry and Molecular Biology, the Biophysical Society, the Federation of American Societies for Experimental Biology, and the Protein Society. He is also a past and present member of the scientific review committees for the National Institutes of Health (NIH) and the National Science Foundation (NSF).

Education B.S., Georgia State University Biophysics Ph.D., Moscow Physico-Technical Institute Biophysical Chemistry and Structural Biology
Scholarly Works:
  • Wafer, LN, Streicher, WW, McCallum, SA, Makhatadze GI (2012) - Thermodynamic and Kinetics Analysis of Peptides Derived from CapZ, NDR, p53, HDM2, and HDM4 Binding to Human S100B. Biochemistry, in press
  • Scian M, Lin JC, Le Trong I, Makhatadze GI, Stenkamp RE, Andersen NH. (2012) - Crystal and NMR structures of a Trp-cage mini-protein benchmark for computational fold prediction. - Proc Natl Acad Sci U S A. 109:12521-12525.
  • Voepel, T. and Makhatadze, G.I. (2012) – Enzyme Activity in Crowded Milieu – PLoS ONE 7: e39418.