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Chemistry and Chemical Biology

Linda B. McGown

Linda B. McGown
Sun, 2010-06-13 02:05 — mcgowl
Name: Linda B. McGown
Title:Professor
Department Chemistry and Chemical Biology
School Science
Website:http://rpi.edu/dept/chem/chem_faculty/profiles/mcgown.html
Bio McGown began her faculty career as a pre-doctoral lecturer at Texas A&M University from 1978-79, and then as an assistant professor of chemistry at California State University, Long Beach from 1979-82. She then joined the Department of Chemistry at Oklahoma State University and was promoted to associate professor with tenure in 1985. She left O.S.U. in 1987 to join the faculty at Duke University where she remained until coming to Rensselaer as professor and department head from 2004-2009. In 2006, she was appointed to the William Weightman Walker Chair in Chemistry and Chemical Biology.

A frequent public speaker, McGown has offered dozens of presentations at universities and conferences throughout the United States, Canada, Latin America and Europe. She has authored or co-authored over 100 refereed journal publications and more than 200 conference presentations. A Fellow of the American Association for the Advancement of Science (AAAS) since 2001, McGown received the Gold Medal Award from the New York Section of the Society for Applied Spectroscopy in 1994. She has served on numerous panels and committees including the National Institutes of Health Bioanalytical Engineering and Chemistry Study Section and the Analytical and Physical Chemistry Grant Selection Committee of the Natural Sciences and Engineering Research Council of Canada. She served as program co-chair for the 1996 Federation of Analytical, Spectroscopy Societies (FACSS) Meeting in Austin and is a member of the Scientific Committee of the Frederick Conference on Capillary Electrophoresis/Proteomics. She has served on the editorial boards of several journals including Chemical and Engineering News, Analytical Chemistry, and Applied Spectroscopy.

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Education Ph.D., Chemistry, University of Washington, 1979 B.S., Chemistry, State University of New York at Buffalo, 1975

Jim Moore

Jim Moore
Sun, 2010-06-13 02:05 — moorej
Name: Jim Moore
Title:Professor
Department Chemistry and Chemical Biology
School Science
Center New York State Center for Polymer Synthesis
Website:http://rpi.edu/dept/chem/chem_faculty/profiles/moore.html
Bio B. S., Chemistry, St John's University, Brooklyn, NY, 1961
Ph. D., Chemistry, Polytechnic Institute of Brooklyn, 1967
Prof. Moore was a National Institutes of Health Postdoctoral Fellow at the University of Mainz, West Germany in 1967 and in 1968 he was a Research Associate at the University of Michigan. In 1969 he joined the faculty of the Chemistry Department of Rensselaer Polytechnic Institute where he is currently Professor of Organic and Polymer Chemistry. He is a member of the American Chemical Society and has been Associate Editor of Macromolecules and Chairman of the Division of Polymer Chemistry of the American Chemical Society. He is the author more than 200 publications, including 6 books and 13 patents, and in 1985 received the American Cyanamid Award for Significant Achievement in Synthesis. In 1999 he received the Presidential Green Chemistry Challenge Award for his work on generating polymers from waste cellulose. In 2011 he was named a Fellow of the American Chemical Society.
Professor Moore's research interests are concentrated in the general area of synthesis and chemical modification of polymeric materials. He is also active in several specific research areas such as the synthesis of radiation sensitive and thermally stable materials for use in the development of new composites and in microelectronic processing. He is developing new approaches to the synthesis of organic polymers as on-chip dielectrics by vapor phase deposition, and has also helped to develop a novel approach to the chromatographic purification of proteins. e has a long term interest in the preparation of novel polymeric materials from renewable natural resources.

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Education Ph.D., Organic-Polymer Chemistry, Polytechnic Institute of Brooklyn, 1967 B.S., Chemistry, St. John's University,1961
Scholarly Works:
  • “Synthesis, Characterization and Properties of Polycarbonate-containing Carboxyl Side Groups”, Ruifeng Zhang and J. A. Moore, Macromolecular Symposia,199 (Polycondensation 2002), 375-390 (2003).
  • “Alkyl-based Selective Displacers for Protein Purification in Ion Exchang Chromatography”, Christopher J. Morrison, J.A. Moore, Steven M. Cramer, Chromatographia, 72 (11/12), 1025-34 (2010).
Recognitions:
  • Fellow of the American Chemical Society
  • 1999 Presidential Green Chemistry Challenge Award co-recipient, United States Environmental Protection Agency, “Economic Conversion of Cellulosic Biomass to Chemicals”.

Mark Platt

Mark Platt
Sun, 2010-06-13 02:05 — plattm
Name: Mark Platt
Title:Assistant Professor
Department Chemistry and Chemical Biology
School Science
Website:http://www.rpi.edu/dept/chem/chem_faculty/profiles/platt.html
Bio Mark Platt completed his doctoral training under the guidance of Professor Donald F. Hunt at the University of Virginia, where he focused on the use of mass spectrometry to identify proteins within biological systems, specifically in the areas of proteomics, protein phosphorylation, and differential analysis.

Following his graduate work, Platt accepted a position as a Senior Research Fellow at the University of Melbourne in Melbourne, Australia. There he was responsible for establishing and managing a functioning proteomics laboratory and for applying this technology to the elucidation of protein expression and signaling pathways in plant systems. He was also responsible for establishing several important external research collaborations and for supervising doctoral students.

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Education Ph.D., Chemistry, University of Virginia, College of Arts & Sciences B.A., Chemistry, Cornell University, College of Arts & Sciences

Chang Ryu

Chang Ryu
Sun, 2010-06-13 02:05 — ryuc
Name: Chang Ryu
Title:Associate Professor
Department Chemistry and Chemical Biology
School Science
Center New York State Center for Polymer Synthesis Rensselaer Nanotechnology Center (RNC)
Website:http://www.rpi.edu/~ryuc/
Bio Career Highlights:
Upon earning his Ph.D. with Tim Lodge at the University of Minnesota , Dr. Ryu served as a postdoctoral researcher with Ed Kramer and Glenn Fredrickson at the University of California , Santa Barbara for nearly two years. He joined Rensselaer in November, 2000 as an assistant professor of chemistry,and was promoted to an Associate Professor in 2006. He has won the NSF CAREER Award (2005), Mettler-Toledo Thermal Analysis Education Grant (2001), the Arthur K. Doolittle Award from the American Chemical Society Division of Polymeric Materials Science and Engineering (1998), and Korea Foundation for Advanced Studies Scholarship (1993 – 1998).

Research Areas:
Macromolecular Separation and Adsorption:
Our group is studying macromolecular separation and adsorption using high performance liquid chromatography (HPLC). We study polymer separation by HPLC and explore its unique applications for rigorous analysis and purification of polymers, block copolymers and functional oligomers. We also pursue a molecular level understanding of polymer/copolymer adsorption in confined geometries in order to gain insights on macromolecular interactions during HPLC. We are mainly interested in separating (co)polymers and oligomers that are synthetically very challenging to obtain as pure samples and/or can have technological implications in nanoscale self-assembly, electro-optical applications, and carbon nanotube fabrication.

Block Copolymer Self-Assembly in Solution and Thin Films:
We are interested in developing a polymer research program in structure-property relationships of multiphase polymer systems, where their performance and applications are closely related to the mesoscopic morphologies. The central theme of my research effort will be the design, synthesis, and characterization of model polymers and the study of their structure-property relationships as in bulk and thin films. We will combine the polymer separation technique using HPLC to obtain pure block copolymers and study their self-assembly in solution and thin films. The ultimate aim will be to guide the rational design of polymeric materials, thus gaining a fundamental understanding in the correlation between properties and structures in multiphase polymers.
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Education Education: Ph.D., Chemical Engineering, University of Minnesota, 1998 B.S., M.S., Chemical Technology, Seoul National University, 1990, 1992

Joseph Warden

Joseph Warden
Sun, 2010-06-13 02:05 — wardej
Name: Joseph Warden
Title:Professor
Department Chemistry and Chemical Biology
School Science
Website:http://rpi.edu/dept/chem/chem_faculty/profiles/warden.html
Bio Warden received his Ph.D. in physical chemistry (specialty: molecular spectroscopy) at the University of Minnesota under the direction of James Bolton. After postdoctoral studies at the Rijksuniversiteit, Leiden in the Netherlands (with L. N. M. Duysens) and the University of California, Berkeley (Melvin Calvin), Dr. Warden joined the chemistry faculty at Rensselaer.

Research Areas:
Our research group applies the techniques of physical and protein chemistry to study the structure and function of biological oxidation-reduction complexes. Electron paramagnetic resonance spectroscopy, time-resolved optical (laser) spectroscopy and electroabsorption (Stark) spectroscopy are typical experimental methodologies practiced in our laboratory.

Although a major focus of my laboratory is the elucidation of the structure and function of the reaction-center protein complexes that catalyze the initial light-driven steps in photosynthesis, collaborative investigations include: characterization of the structures and mechanism of radical products in irradiated ultrahigh molecular weight polyethylene (polymer physical chemistry, medical applications); oxygen radical metabolism in cellular processes (aging and cell apoptosis) and function and structures of de novo design proteins.

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Education Ph.D., Physical Chemistry, University of Minnesota
Scholarly Works:
  • Charge Recombination between P700+ and A1- Occurs Directly to the Ground State of P700 in a Photosystem I Core Devoid of Fx, Fb and Fa. P. V. Warren, J. H. Golbeck and J. T. Warden (1993) Biochemistry 32, 1835. Investigation of the Ammonium Acetate Inhibition of Oxygen Evolution by Photosystem II. D. J. MacLachlan, J. H. A. Nugent, J. T. Warden and M. C. W. Evans (1995) Biochim. Biophys. Acta 1188, 325-334. Electron Spin Resonance and Electrospray Ionization Mass Spectroscopic Studies of the Interaction of Alkali and Alkaline Earth Cations with Manganese Bis(Mu-Oxo) Dimers. C. P. Horwitz, J. T. Warden and S. T. Weintraub (1996) Inorganica Chimica Acta 246, 311-320. An Extended X-Ray Absorption Fine Structure Study of bis(m-oxo) Bridged Dinuclear Manganese Co-ordination Compounds Containing Alkali- and Alkaline-earth-metal Cations in a Crown Ether Moiety. S. Turconi, C. P. Horwitz, Y. Ciringh, S. T. Weintraub, J. T. Warden, J. H. A. Nugent and M. C. W. Evans (1997) J. Chem. Soc., Dalton Trans. 4075 -4082. An Exafs Study Of Bis(Mu-Oxo) Bridged Dinuclear Manganese Coordination Compounds As Models For The Manganese Complex Of Photosystem II. S. Turconi, C. P. Horwitz, Y. Ciringh, S. T. Weintraub, J. T. Warden, J. H. A. Nugent and M. C. W. Evans (1997) Journal De Physique IV 7, 603-606.

Mark Wentland

Mark Wentland
Sun, 2010-06-13 02:05 — wentmp
Name: Mark Wentland
Title:Professor
Department Chemistry and Chemical Biology
School Science
Website:http://www.rpi.edu/dept/chem/chem_faculty/profiles/wentland.html
Bio Mark Wentland began his career in drug discovery in 1970 when he joined the medicinal chemistry department at Sterling Winthrop Inc. He earned his Ph.D. in synthetic organic chemistry in 1970 at Rice University under the direction of the late Professor Robert V. Stevens. During his 24 years at Sterling Winthrop, he held various positions of scientific and administrative responsibility with his last positions being Sterling Winthrop Fellow and Oncology Discovery Co-Chair. During the period 1971-1994, he was Adjunct Professor of Chemistry at Rensselaer Polytechnic Institute in Troy, NY where he taught over 30 graduate-level organic and medicinal chemistry courses.
In 1994, he joined the chemistry faculty at Rensselaer as Professor of Chemistry. At Rensselaer, he maintains a federally-funded research program in medicinal chemistry aimed at identifying novel, long-acting oral agents to treat cocaine addiction in humans. He recently developed the course Drug Discovery, where students learn and practice modern techniques of drug discovery. He holds the concurrent position of Adjunct Professor - Center for Neuropharmacology & Neuroscience at Albany Medical College where his responsibilities include collaborative neuroscience research with AMC scientists and presentation of lectures relating to medicinal chemistry.
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Education Doctoral: Rice University, Houston, TX, 1966-1970 Ph.D., Organic Chemistry [Thesis Advisor: Dr. R. V. Stevens (deceased)] Undergraduate: Central Connecticut State University, New Britain, CT, 1962-1966 B.S., Chemistry (Mathematics-minor)
Scholarly Works:
  • Wentland, M. P.; Lou, R.; Lu, Q.; Bu, Y.; Denhardt, C.; Jin, J.; Ganorkar, R.; VanAlstine, M. A.; Guo, C.; Cohen, D. J.; Bidlack, J. M. " Syntheses of novel high affinity ligands for opioid receptors" Bioorg. Med. Chem. Lett. 2009, 19, 2289–2294.
  • Conroy, J. L.; Fang, C.; Gu, J.; Zeitlin, S. O.; Yang, W.; Yang, J.; VanAlstine, M. A.; Nalwalk, J. W.; Albrecht, P. J.; Mazurkiewicz, J. E.; Snyder-Keller, A.; Shan, Z.; Zhang, S.; Wentland, M. P.; Behr, M.; Knapp, B. I.; Bidlack, J. M; Zuiderveld, O. P.; Leurs, R.; Ding, X.; Hough, L. B. "Opioids Activate Brain Analgesic Circuits Through Cytochrome P450/Epoxygenase Signaling." Nature Neuroscience, 2010, 13, 284-286.
  • Plus 109 others (see SciFinder Scholar)