bioreactors and biosensors

James A. Cooper
Name: James A. Cooper
Title:Assistant Professor
Department Biomedical Engineering
School Engineering
Center Center for Biotechnology and Interdisciplinary Studies (CBIS)
Bio Dr. Cooper received his Ph.D. degree from Drexel University and was a National Research Council (NRC) Post-Doctoral Associate at the National Institutes of Standards and Technology (NIST). At NIST, he specialized in the area of tissue engineering that included investigations with bioreactors, bioimaging and 3-D scaffold fabrication. In 2007, he became an inaugural 2006 Hartwell Foundation Fellow at the University of Pennsylvania’s Tissue Microfabrication Laboratory (TML) in the Department of Bioengineering. At the TML, he specialized in studies investigating the interaction between cells and their microenvironments. He used novel microfabrication tools to monitor the interactions of mesenchymal stem cells in order to better understand how the cells function under static conditions as they commit to chondrogenic and osteogenic lineages in the same cellular mass for the development of an osteochondral implant.

Dr. Cooper reviews for several journals including the Journal of Biomedical Materials Research, Acta Biomaterialia and Journal of Polymer Research.

Dr. Cooper’s interests and the general areas of research of his laboratory include the multidisciplinary areas of Biomaterials, Cell and Tissue Engineering, Orthopedics, Stem Cell Biology, Materials Fabrication, Bioimaging, Bioreactors and Biosensors.
Details
Education Ph.D. Biomedical Science (Drexel University, 2002) M.S. Materials (Pennsylvania State University, 1993) B.A. Chemistry (Lincoln University, 1989)
Scholarly Works:
  • Engineering controllable anisotropy in electrospun biodegradable nanofibrous scaffolds for musculoskeletal tissue engineering (2007)
  • Osteogenic differentiation of dura mater stem cells cultured in vitro on three-dimensional porous scaffolds of poly(
  • Perfusion Flow Bioreactor for 3-D In Situ Imaging: Investigating Cell-Biomaterial Interactions (2007)
  • Systematic Investigation of Porogen Size and Content on Scaffold Morphometric Parameters and Properties (2007)
  • A Systematic Study on Fabrication and Characterization of Electrospun Poly(alpha-hydroxy ester) based Nanofibrous Scaffolds (2006)
  • Biomimetic Tissue-Engineered Anterior Cruciate Ligament Replacement (2007)
  • Tissue Engineering of Bone and Ligament A 15-year Perspective (2006)
  • Encapsulated Chondrocyte Response to Pulsatile Flow Bioreactor (2007)
  • Tissue Engineering Scaffolds Based on Photocured Dimethacrylate Polymers for In Vitro Optical Imaging (2006)