medicinal chemistry

Mark Wentland

Sun, 2010-06-13 02:05 — wentmp

Name:	Mark Wentland
Title:	Professor
Department	Chemistry and Chemical Biology
School	Science
Website:	http://www.rpi.edu/dept/chem/chem_faculty/profiles/wentland.html

Bio Mark Wentland began his career in drug discovery in 1970 when he joined the medicinal chemistry department at Sterling Winthrop Inc. He earned his Ph.D. in synthetic organic chemistry in 1970 at Rice University under the direction of the late Professor Robert V. Stevens. During his 24 years at Sterling Winthrop, he held various positions of scientific and administrative responsibility with his last positions being Sterling Winthrop Fellow and Oncology Discovery Co-Chair. During the period 1971-1994, he was Adjunct Professor of Chemistry at Rensselaer Polytechnic Institute in Troy, NY where he taught over 30 graduate-level organic and medicinal chemistry courses.
In 1994, he joined the chemistry faculty at Rensselaer as Professor of Chemistry. At Rensselaer, he maintains a federally-funded research program in medicinal chemistry aimed at identifying novel, long-acting oral agents to treat cocaine addiction in humans. He recently developed the course Drug Discovery, where students learn and practice modern techniques of drug discovery. He holds the concurrent position of Adjunct Professor - Center for Neuropharmacology & Neuroscience at Albany Medical College where his responsibilities include collaborative neuroscience research with AMC scientists and presentation of lectures relating to medicinal chemistry.

Details

Funding Agency

NIH-NIDA

Signature_Thrust

Biotechnology

Keywords

Education Doctoral: Rice University, Houston, TX, 1966-1970 Ph.D., Organic Chemistry [Thesis Advisor: Dr. R. V. Stevens (deceased)] Undergraduate: Central Connecticut State University, New Britain, CT, 1962-1966 B.S., Chemistry (Mathematics-minor)

Scholarly Works:

Wentland, M. P.; Lou, R.; Lu, Q.; Bu, Y.; Denhardt, C.; Jin, J.; Ganorkar, R.; VanAlstine, M. A.; Guo, C.; Cohen, D. J.; Bidlack, J. M. " Syntheses of novel high affinity ligands for opioid receptors" Bioorg. Med. Chem. Lett. 2009, 19, 2289–2294.
Conroy, J. L.; Fang, C.; Gu, J.; Zeitlin, S. O.; Yang, W.; Yang, J.; VanAlstine, M. A.; Nalwalk, J. W.; Albrecht, P. J.; Mazurkiewicz, J. E.; Snyder-Keller, A.; Shan, Z.; Zhang, S.; Wentland, M. P.; Behr, M.; Knapp, B. I.; Bidlack, J. M; Zuiderveld, O. P.; Leurs, R.; Ding, X.; Hough, L. B. "Opioids Activate Brain Analgesic Circuits Through Cytochrome P450/Epoxygenase Signaling." Nature Neuroscience, 2010, 13, 284-286.
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