Center for Modeling, Simulation and Imaging in Medicine (CEMSIM)

Kurt S. Anderson
Name: Kurt S. Anderson
Title:Professor and Associate Dean for Undergraduate Studies
Department Mechanical Aerospace and Nuclear Engineering
Center Center for Modeling, Simulation and Imaging in Medicine (CEMSIM)
Website:http://www.rpi.edu/~anderk5/
Bio After receiving his BS degree in mechanical engineering from the University of California at Berkeley in 1982, Dr. Anderson went on to earn a MS in the area of dynamic systems and control from the same institution in 1984. He then spent the next two years working in the areas of dynamics, structural dynamics, and controls for TRW Space and Technology in Redondo Beach, California.
After this period, he entered the Ph.D. program in Applied and Computational Mechanics at Stanford University, earning his degree in 1990. Dr. Anderson then accepted a position as researcher and principal dynamics engineering at TRW where he was associated with various spacecraft and research programs. In late 1991 Dr. Anderson was invited to Germany for a two-year period as a visiting scholar, lecturer, and research fellow at the Technische Hochscule - Darmstadt. In 1993 he joined the faculty of the Department of Aerospace Engineering, Applied Mechanics, and Aviation at The Ohio State University, in Columbus where he remained until coming to Rensselaer
Details
Education Ph.D. Stanford University
Scholarly Works:
  • A Dynamics Simulation of Multibody Systems Using a New State-Time Methodology
  • Parallel Logarithmic Order Algorithm for General Multibody System Dynamics (2004)
  • A State-Time Formulaton for Dynamics Systems Simulation Using Massively Parallel Computing Resources
  • Order(n+m): Direct Differentiation Determination of Design Sensitivity for Constrained Multibody Dynamic Systems (2004)
  • A Generalized Recursive Coordinate Reduction Method for Multibody Dynamic Systems (2003)
  • Improved Order-n Performance Algorithm for the Simulation of Constrained Multi-Rigid-Body Systems (2003)
  • Recursive Sensitivity Analysis for Constrained Multi-rigid-body Dynamic Systems Design Optimization (2002)
  • Analytical Full-Recursive Sensitivity Analysis for Multibody Chain Systems (2002)
  • Domain Approximation and Deterministic Progression in Genetic Crossover (2001)
  • Low Operational Order Analytic Sensitivity Analysis for Tree-Type Multibody Dynamic Systems (2001)
Recognitions:
  • Fellow ASME
  • Associate Fellow AIAA
Diana-Andra Borca-Tasciuc
Name: Diana-Andra Borca-Tasciuc
Title:Associate Professor
Department Mechanical Aerospace and Nuclear Engineering
School Engineering
Center Center for Modeling, Simulation and Imaging in Medicine (CEMSIM)
Website:http://homepages.rpi.edu/~borcad/CV_Diana_Borca_Tasciuc.pdf
Bio D.-A. Borca-Tasciuc received her B.S. in Physics from Bucharest University in 1996, and M.S. and PhD. in Mechanical Engineering from University of California at Los Angeles in 2001 and respectively 2005. She was a visiting student at Massachusetts Institute of Technology in 2001 and 2002 and Rensselaer Polytechnic Institute between 2003 and 2005. She joined RPI's Mechanical Engineering Department as an assistant professor in 2006.
Details
Education Ph.D. University of California at Los Angeles
Suvranu De
Name: Suvranu De
Title:Department Head, Professor and Director, CeMSIM
Department Biomedical Engineering IT and Web Science Mechanical Aerospace and Nuclear Engineering
School Engineering
Center Center for Modeling, Simulation and Imaging in Medicine (CEMSIM)
Website:http://www.rpi.edu/~des/
Bio
  • Professor, MANE, BME and ITWS Departments, RPI
    2011 - present
  • Director, Center for Modeling, Simulation and Imaging in Medicine (CeMSIM), RPI
    2010 - present
  • Associate Professor, MANE, BLE and ITWS Departments, RPI
    2007 - 2010
  • Assistant Professor, MANE Department, RPI
    2002 - 2007
  • Research Scientist, Research Laboratory of Electronics, MIT
    Oct 2000 - Dec 2001
    • Fast computational tools for MEMS design
    • Multimodal medical simulations
  • Graduate Research Assistant, Department of Mechanical Engineering, MIT
    May 1997 - Sep 2000
    • Meshfree Methods: Method of Finite Spheres
    • Virtual environments for medical simulation
    • Biomechanics of touch
  • Research Associate, Department of Mechanical Engineering, Indian Institute of Science, Bangalore
    Sept 1993 - Jan 1995
    • FE algorithms for large deformation elastoplastic boundary value problems
Details
Education Sc.D. Massachusetts Institute of Technology
Scholarly Works:
  • The method of finite spheres (2000)
  • De, S. and Bathe, K. J., The method of finite spheres with improved numerical integration(2001)
  • De, S. and Bathe, K. J., Towards an efficient meshless computational technique: the method of finite spheres (2001)
  • Displacement/ pressure mixed interpolation in the method of finite spheres (2001)
  • On the method of finite spheres in applications: towards the use with ADINA and a surgical simulator (2003)
  • Hierarchical tree-based discretization in the method of finite spheres (2003)
  • Efficient computation of drag forces on micro-machined devices using a boundary integral equation-based solver (2003)
  • Physically-based real time simulation of soft tissues in multimodal medical simulations
  • Towards an automatic discretization scheme for the method of finite spheres and its coupling with the finite element method
  • The role of haptics in medical simulations
  • A unified approach to multimodal rendering of heterogeneous scenes using point clouds
  • A finite element mode
Xavier Intes
Name: Xavier Intes
Title:Associate Professor
Department Biomedical Engineering
School Engineering
Center Center for Biotechnology and Interdisciplinary Studies (CBIS) Center for Engineering-based Patient Modeling (CEPM) Center for Modeling, Simulation and Imaging in Medicine (CEMSIM) Scientific Computation Research Center (SCOREC)
Website:http://intes-lab.bme.rpi.edu/index.shtml
Bio Xavier Intes received a Ph.D. degree in 1998 in physics from the University of Bretagne Occidentale (France) for his contributions in characterization of propagation of optical scalar waves in highly diffuse medium. He then joined Prof Chance laboratory in 1999 as a postdoctoral fellow at the University of Pennsylvania. He held simultaneously postdoctoral appointments in the departments of Biochemistry and Biophysics, of Radiology under the mentorship of Prof Chance and the department of Astronomy and Physics under the mentorship of Prof Arjun Yodh. In 2001, he acted as the Director of Research of the Medical Diagnostic Research Foundation, Philadelphia, USA, and the Director of Research of Optical Devices Inc., Philadelphia, USA. In 2003 he joined Advanced Research Technologies Inc as as ART's Chief Scientist.

Details
Education Ph.D. Physics (Universite de Bretagne Occidentale (France), 1998)
M.S. Physics (Universite de Bretagne Occidentale, 1994)
B.S. Physics (Universite de Bretagne Occidentale, 1992)
Scholarly Works:
  • h-index: 20; Citations> 1400 (http://scholar.google.com/citations?user=J5KmM0YAAAAJ&hl=en)
  • V Venugopal, J Chen, M Barrosso and X Intes, “Quantitative tomographic imaging of intermolecular FRET in small animals,” Biomedical Optics Express, 3(12), 3161-3175 (2012)
  • M Pimpalkhare, J Chen, V Venugopal and X Intes, “Ex Vivo Fluorescence Molecular Tomography of the Spine,” International Journal of Biomedical Imaging, 942326 (2012)
  • J Chen, Q Fang and X Intes, “Mesh-based Monte Carlo Method in Time-domain Widefield Fluorescence Molecular Tomography,” Journal of Biomedical Optics 17(10), 106009 (2012).
  • X Intes, V Venugopal, J Chen and F Azar, “Multimodal diffuse imaging system,” in Biomedical Optical Imaging Techniques: Design and Applications, Springer, Chapter 7:351-374(2012).
  • L Zhao, V Lee, G Dai and X Intes, “Mesoscopic Fluorescence Molecular Tomography of Tissue Engineered Vascular Construct,” Biomaterials 33 (21), 5325–5332 (2012).
  • V Venugopal and X Intes, “Recent advances in optical mammography,” Current Medical Imaging Reviews 8(4), 244-259 (2012).
  • X Intes and F S Azar, “Advances in optical mammography,” in Advanced Optical Imaging Technologies for Clinical Medicine, Editors N Iftimia, W Brugge, D Hammer, Wiley &Sons, Chapter 11: 307-336 (2011).
  • J Chen and X Intes, “Comparison of Monte Carlo Methods for Fluorescence Molecular Tomography - Computational Efficiency,” Medical Physics 38 (10), 5788-5798 (2011).
  • J Chen , V Venugopal and X Intes, “A Monte Carlo based method for fluorescence tomographic imaging with lifetime multiplexing using time gates,” Biomedical Optics Express 2, 871-886 (2011).
  • V Venugopal, J Chen , F Lesage and X Intes, “Full-field time-resolved fluorescence tomography of small animals,” Optics Letters 35, 3189-3191 (2010).
  • V Venugopal, J Chen and X Intes, “Development of an optical imaging platform for functional imaging of small animals using wide-field excitation,” Biomedical Optics Express 1, 143-156 (2010).
  • J Chen , V Venugopal, F Lesage and X Intes, “Time Resolved Diffuse Optical Tomography with patterned light illumination and detection,” Optics Letters 35, 2121-2123 (2010).
  • S Belanger, M Abran, X Intes, C Casanova and F Lesage, “Real time Diffuse Optical Tomography based on Structured Illumination,” Journal of Biomedical Optics 15, 016006 (2010).
  • J Chen and X Intes, “Time-gated perturbation Monte Carlo for whole body functional imaging in small animals,” Optics Express 17, 19566–19579 (2009).
  • X Intes and F S Azar, “Introduction to Clinical Optical Imaging,” in Translational Multimodality Optical Imaging, Editors F. Azar and X. Intes, Chapter 1: 1-19 (2008).
  • B. Alacam, B. Yazici, X. Intes and B. Chance, “Pharmacokinetic-rate images of indocyanine green for breast tumors using near-infrared optical methods,” Phys. Med. Biol. 53, 837-859 (2008).
  • Book: Translational Multimodality Optical Imaging, Fred S Azar and Xavier Intes Editors, Artech House Publishing, 386 pages, 2008.
  • M. Guven, E. Giladi, B. Yazici, K. Kwon and X. Intes, “Effect of discretization error and adaptive mesh generation in diffuse optical absorption imaging: Part I,” Inverse Problem 23, 1115-1133 (2007).
  • M. Guven, E. Giladi, B. Yazici, K. Kwon and X. Intes, “Effect of discretization error and adaptive mesh generation in diffuse optical absorption imaging: Part II,” Inverse Problems 23, 1133-1160 (2007).
Recognitions:
  • NSF CAREER AWARD
  • SPIE: senior member
Shiva Kotha
Name: Shiva Kotha
Department Biomedical Engineering
School Engineering
Center Center for Biotechnology and Interdisciplinary Studies (CBIS) Center for Modeling, Simulation and Imaging in Medicine (CEMSIM)
Bio Dr Kotha obtained his undergraduate training in Mechanical Engineering from Regional Engineering College, Tiruchirappalli (now NIT, Trichy) and his Ph.D. in Biomedical engineering from Rutgers University and University of Medicine and Dentistry of New Jersey. He served as a post-doctoral researcher in Aerospace and Mechanical Engineering at the University of Notre Dame and in Orthopaedic Surgery at Washington University in St Louis. Dr Kotha served as faculty at the dental school of the University of Missouri-Kansas City and in Mechanical Engineering at the University of Connecticut prior to joining Rensselaer Polytechnic Institute. Dr Kotha has worked on the experimental and theoretical aspects of bone tissue damage, adaptation and repair, as well as the development of novel materials that can be used to support implants.

Dr Kotha’s research interests lie broadly in the area of developing novel multi-functional materials and devices to understand and control cell/ tissue function. His research areas include cell and tissue mechanics, multi-functional materials, and the development of minimally invasive modalities for imaging and treatment.
For example, in the area of bone biomechanics, Dr Kotha’s group studies the role of mechanical loading on damage and repair to bone at multiple length scales. They characterize how mineral and organic in bone support its deformation as load is applied. When this is combined with novel non-invasive ultrasound based technologies being developed, the overall goal is to make devices that can be used to monitor the risk of bone failure at specific sites. They also evaluate how cells sense deformation of bone and what molecular pathways are activated in response to loading. These studies can be used to develop therapeutics that can be used to create new bone at sites where it is required. In summary, his research on bone will enable the development of novel devices that can enhance new bone formation at specific sites while assaying its fracture risk.
Details
Education Ph.D., Rutgers University, 2000
Antoinette M. Maniatty
Name: Antoinette M. Maniatty
Title:Professor
Department Mechanical Aerospace and Nuclear Engineering
School Engineering
Center Center for Automation Technologies and Systems (CATS) Center for Inverse Problems (IPRPI) Center for Modeling, Simulation and Imaging in Medicine (CEMSIM) Scientific Computation Research Center (SCOREC)
Website:http://www.rpi.edu/~maniaa
Bio

After receiving her B.S. degree in Mechanical Engineering with highest honors from Rensselaer Polytechnic Institute in 1987, Antoinette Maniatty went on to earn two M.S. degrees in Mechanical Engineering, one from the University of Minnesota in 1988 and a second from Cornell University in 1990, followed by a Ph.D. from Cornell in 1991. After spending one year as a Visiting Lecturer at the University of Natal in Durban, South Africa, she joined the faculty at Rensselaer in 1992. She was the Clare Boothe Luce Assistant Professor from 1992-1997. She was one of four women scientists and engineers nationwide to be awarded a Luce fellowship by the Luce Foundation in 1992. In 1993, she received a National Science Foundation Young Investigator Award. She was a member of the Defense Science Study Group in 2000 and 2001. In 2001, she was the first Loewy Visiting Professor in the Materials Science and Engineering Department at Lehigh University. In 2005, she was named a Fellow of the ASME. Maniatty is a member of the ASME, SME, ASEE, Tau Beta Pi, Pi Tau Sigma, and Sigma Xi.

Details
Education Ph.D. Cornell University
Scholarly Works:
  • J. D. Hochhalter, D. J. Littlewood, M. G. Veilleux, J. E. Bozek, A. M. Maniatty, A. D. Rollett, and A. R. Ingraffea, "A geometric approach to modeling microstructurally small fatigue crack formation: III. Development of a semi-empirical model for nucleation." Modell. Simul. Mater. Sci. Eng., vol. 19, 035008 (27pp), 2011.
  • H. Zhang, G. S. Cargill III, and A. M. Maniatty, "Thermal strains in passivated aluminum and copper conductor lines." J. Mat. Res. , vol. 26, 633-639, 2011.
  • A. M. Maniatty, G. S. Cargill III, Laura E. Moyer, and Chia-Ju Yang, "Investigation of thermal stress variability due to microstructure in thin aluminum films." Journal of Applied Mechanics , vol. 78, 011012-1-9, 2011.
  • T. Irisawa, G. S. Cargill III, K. J. Hwang, and A. M. Maniatty, "Viscous elongation of glass rods: Experiments, Simulation, and Analysis." J. Appl. Phys. , vol. 108, 113515, 2010.
  • J. D. Hochhalter, D. J. Littlewood, R. J. Christ Jr., M. G. Veilleux, J. E. Bozek, A. R. Ingraffea, and A. M. Maniatty, "A geometric approach to modeling microstructurally small fatigue crack formation, part II: simulation and prediction of crack nucleation in AA 7075-T651." Modelling and Simulation in Materials Science and Engineering , vol. 18, 045004, 2010.
  • Karel Matous and Antoinette M. Maniatty, "Multiscale modeling of elasto-viscoplastic polycrystals subjected to finite deformations." Interaction and Multiscale Mechanics , vol. 2, 375-396, 2009.
  • Eunyoung Park and Antoinette M. Maniatty,"Finite element formulation for shear modulus reconstruction in transient elastography." Inverse Problems in Science and Engineering, vol. 17, 605 - 626, 2009.
  • Hongqing Zhang, G. Slade Cargill III, Youzhang Ge, Antoinette M. Maniatty, and W. Liu, "Strain evolution in Al conductor lines during electromigration." Journal of Applied Physics, vol. 104, 123533, 2008.
  • J. E. Bozek, J. D. Hochhalter, M. G. Veilleux, M. Liu, G. Heber, S. D. Sintay, A. D. Rollett, D. J. Littlewood, A. M. Maniatty, H. Weiland, R. J. Christ Jr., J. Payne, G. Welsh, D. G. Harlow, P. A. Wawrzynek, and A. R. Ingraffea, "A geometric approach to modeling microstructurally small fatigue crack formation, part I: probabilistic simulation of constituent particle cracking in AA 7075-T651." Modelling and Simulation in Materials Science and Engineering, vol. 16, 065007, 2008.
  • Antoinette M. Maniatty, David J. Littlewood, and Jing Lu, "Polycrystal simulations investigating the effect of additional slip system availability in a 6063 aluminum alloy at elevated temperatures." Journal of Engineering Materials and Technology, vol. 130, 021019-1-9, 2008.
  • Park, E. and Maniatty, A.M., "Shear modulus reconstruction in dynamic elastography: Time harmonic case." Physics in Medicine and Biology , vol. 51, 3697-3721, 2006.
  • Picu, R.C., Vincze, G., Ozturk, F., Gracio, J.J., Barlat, F., and Maniatty, A.M., "Strain rate sensitivity of the commercial aluminum alloy AA5182-O." Materials Science and Engineering A, vol. 390, 334-343, 2005.
  • Ramesh, B. and Maniatty, A.M., "Stabilized finite element formulation for finite elastic-plastic deformations." Computer Methods in Applied Mechanics and Engineering, vol. 194, 775-800, 2005.
  • Matous, K. and Maniatty, A.M., "Finite element formulation for modeling large deformations in elasto-viscoplastic polycrystals." International Journal for Numerical Methods in Engineering, vol. 60, 2312-2333, 2004.
Recognitions:
Saroj K. Nayak
Name: Saroj K. Nayak
Title:Professor
Department Physics, Applied Physics & Astronomy
School Science
Center Center for Integrated Electronics (CIE) Center for Modeling, Simulation and Imaging in Medicine (CEMSIM) The Focus Center New York Rensselaer: Interconnections for Gigascale Integration
Website:http://homepages.rpi.edu/~nayaks/
Bio Dr. Saroj K. Nayak graduated from Jawaharlal Nehru University, India in 1995, with a Ph.D. degree in physical science. Before joining the faculty at Rensselaer in 2000 Dr. Nayak was a Princeton Materials Institute Jr. Fellow at Princeton University. He is currently a Professor in the Physics department at Rensselaer.


His research interests lie at the interface of physics, chemistry and engineering, with principle areas of focus on the study of atomic and electronic structures of matters using ab initio electronic structure calculation methods with classical and quantum molecular dynamics simulations and Monte Carlo methods.

The two major recent focuses of Dr. Nayak's research are -- study of nanostructured materials and simulations of biological molecules using electronic structure methods.

Details
Education Ph.D., Physical Science, Jawaharlal Nehru University, India, 1995
Assad Anshuman Oberai
Name: Assad Anshuman Oberai
Title:Professor
Department Mechanical Aerospace and Nuclear Engineering
School Engineering
Center Center for Modeling, Simulation and Imaging in Medicine (CEMSIM)
Website:http://www.rpi.edu/~oberaa/
Bio Assad Oberai received his PhD. in Mechanical Engineering from Stanford University in 1998. His doctoral work involved developing accurate and efficient finite element methods for solving time-harmonic, wave propagation problems in unbounded domains. As a post-doctoral researcher at Stanford University he developed multiscale formulations of large eddy simulation for modeling turbulent flows and numerical methods for predicting noise generated by such flows. In 2001, Dr. Oberai joined Boston University as an Assistant Professor and in 2006 he moved to the Mechanical, Aerospace and Nuclear Engineering Department at RPI. Here, he continues to work on numerical methods for problems with multiple scales and inverse problems.
Details
Education Ph.D. Stanford University
Scholarly Works:
  • Elastic modulus imaging: some exact solutions of the compressible elastography inverse problem. (2007)
  • Coupling between elastic strain and interstitial fluid flow: ramifications for poroelasticity imaging. (2006)
  • A Dynamic Multiscale Viscosity Method for the Spectral Approximation of Conservation Laws. (2006)
  • Variational Formulation of the Germano Identity for the Navier-Stokes Equations. (2005)
  • A Dynamic Approach for Evaluating Parameters in a Numerical Method (2005)
  • Acoustic Eigenvalues of Rectangular Rooms with Arbitrary Wall Impedances using the Interval Newton/Generalized Bisection Method (2005)
  • Evaluation of the Adjoint Equation Based Algorithm for Elasticity Imaging. (2004)
  • Sensitivity of the Scale Partition for Variational Multiscale LES of Channel Flow (2004)
  • An Application of Shape Optimization in the Solution of Inverse Acoustic Scattering Problems. (2004)
  • A Krylov subspace projection method for simultaneous solution of Helmholtz problems at multiple frequencies. (2003)
Richard Radke
Name: Richard Radke
Title:Associate Professor
Department Electrical, Computer, and Systems Engineering
School Engineering
Center Center for Automation Technologies and Systems (CATS) Center for Modeling, Simulation and Imaging in Medicine (CEMSIM) Center for Sub-surface Sensing and Imaging Systems (CenSSIS) Smart Lighting Engineering Research Center (ERC)
Website:http://www.ecse.rpi.edu/~rjradke
Bio Dr. Radke joined the Electrical, Computer, and Systems Engineering department at Rensselaer Polytechnic Institute in August, 2001, where he is now an Associate Professor. His current research interests include computer vision problems related to modeling 3D environments with visual and range imagery, designing and analyzing large camera networks, and machine learning problems for radiotherapy applications. He is affiliated with the NSF Engineering Research Center for Subsurface Sensing and Imaging Systems (CenSSIS), the DHS Center of Excellence on Explosives Detection, Mitigation and Response (ALERT), and Rensselaer's Experimental Media and Performing Arts Center (EMPAC). He received an NSF CAREER award in March 2003 and was a member of the 2007 DARPA Computer Science Study Group. He is a Senior Member of the IEEE and an Associate Editor of IEEE Transactions on Image Processing. In Fall 2012, Cambridge University Press will publish his textbook Computer Vision for Visual Effects.
Details
Education Ph.D. Electrical Engineering (Princeton University), M.A. Computational and Applied Mathematics (Rice University), B.A. Computational and Applied Mathematics (Rice University)