Filbert Totsingan

About

Dr. Totsingan received his M.S. in Industrial Chemistry and his Ph.D. in Organic and Bioorganic Chemistry with honors from the University of Parma (Italy) working with Prof. Rosangela Marchelli and Prof. Roberto Corradini in designing new biosensors (fluorescent peptide nucleic acids, PNAs) for nucleic acids detection. After a year postdoctoral research working on the amplification of chirality in peptide nucleic acids (PNAs) with Prof. Mark Green (Professor Emeritus, NYU School of Engineering), he then moved to NYU Chemistry Department where he spent five years with Prof. Neville Kallenbach (Professor Emeritus) on the design, synthesis and antimicrobial activity testing of short linear and dendrimeric antimicrobial peptides, as well as amphiphilic unimolecular peptide nanoparticles that mimic the structure of host defense peptides (HDPs), but have higher/similar antimicrobial activity and lower cytotoxicity. Dr. Totsingan joined Rensselaer Polytechnic Institute (RPI) in 2014 working with Prof. Richard Gross on the use of enzymes such as proteases, lipases and cutinases as catalysts for the preparation/selective modification of biologically active polymers (e.g. peptides) and small molecules (e.g. glycolipids) and their use as potential candidates for materials, biomedical and health-related applications. His research interest also involves the preparation of new generation of unimolecular polymer nanoparticles for medical imaging, drug/gene delivery, tissue engineering, antimicrobials and adhesives.

Research

Other Focus Areas

Organic and Materials Chemistry, Biopolymers with focus on nucleic acids and peptides, Unimolecular polymer nanoparticles , Biocatalysis

Publications

The following is a selection of recent publications in Scopus. Filbert Totsingan has 29 indexed publications in the subjects of Chemistry, Biochemistry, Genetics and Molecular Biology, Materials Science.

Rebecca T. Miceli, Filbert Totsingan, Tasnim Naina, Samita Islam, Jonathan S. Dordick, David T. Corr, Richard A. Gross
ACS Omega
, 8
, 2023
, pp.14610-14620
.
Cody B. Edson, Melinda Liu, Filbert Totsingan, Evan O’Berg, John Salvucci, Uyen Dao, Sagar D. Khare, Richard A. Gross
Biomacromolecules
, 24
, 2023
, pp.1798-1809
.
Shuguftha Naz, Tuhina Banerjee, Filbert Totsingan, Kalee Woody, Richard A. Gross, Santimukul Santra
Nanotheranostics
, 5
, 2021
, pp.391-404
.
Fan Yang, Filbert Totsingan, Elliott Dolan, Sagar D. Khare, Richard A. Gross
ACS Omega
, 5
, 2020
, pp.4403-4414
.
Robert Centore, Filbert Totsingan, Anna Christina Amason, Samantha Lyons, R. Helen Zha, Richard A. Gross
Biomacromolecules
, 21
, 2020
, pp.493-507
.
Alexis M. Ziemba, Keith P. Lane, Bailey Balouch, Anthony R. D'Amato, Filbert Totsingan, Richard A. Gross, Ryan J. Gilbert
ACS Applied Bio Materials
, 2
, 2019
, pp.3153-3158
.
Patricia Diaz-Rodriguez, Hongyu Chen, Joshua D. Erndt-Marino, Fei Liu, Filbert Totsingan, Richard A. Gross, Mariah S. Hahn
ACS Applied Bio Materials
, 2
, 2019
, pp.601-612
.
Ahmad S. Arabiyat, Patricia Diaz-Rodriguez, Josh D. Erndt-Marino, Filbert Totsingan, Shekar Mekala, Richard A. Gross, Mariah S. Hahn
ACS Applied Bio Materials
, 2
, 2019
, pp.118-126
.
Ahmad S. Arabiyat, Patricia Diaz-Rodriguez, Josh D. Erndt-Marino, Filbert Totsingan, Shekar Mekala, Richard A. Gross, Mariah S. Hahn
Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
, 40
, 2019
, pp.684
.

View All Scopus Publications

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