Peter J. Bonitatibus


The most recent scientific contributions by Prof. Bonitatibus are in the field of contrast media for diagnostic imaging, specifically intravenous nanoparticle-based agents for computed tomography (CT). He is credited with invention of a portfolio of intravenously administered CT contrast agents that comprise a tantalum oxide nanoparticle core coated with a biocompatible siloxane polymer shell. Prof. Bonitatibus has been funded by the NIH for developing these agents dating back to 2013. He is currently funded by the NIH, NSF, and private industry. He has authored 45 technical publications, holds 15 United States issued patents, and appeared in more than 30 presentations at national and local venues.

Prof. Bonitatibus also has more than 15 years of industrial experience as a Senior Scientist at GE Global Research where he was an Independent Contributor and Project Leader, as well as a Principal Investigator for an NIH grant in conjunction with Prof. B. Yeh at UCSF on R01-EB015476 entitled "Nanoparticle CT Contrast Agents for Reduced Radiation Dose and New Imaging Applications" (2013-2017). He has been a co-investigator on 5 awards from the Department of Energy in the last 10 years, the most significant of which was in the area of electrocatalysis for energy storage with Prof. W. Jones at the Univ. of Rochester (DOE DE-SC0001055, 2009-2014).

As a postdoctoral researcher, Prof. Bonitatibus spent two years at MIT in the labs of Prof. R. Schrock (Nobel Laureate in Chemistry, 2005) where he focused on the design, synthesis, and discovery of living organometallic olefin (cationic) polymerization catalysts. He published a total of 16 journal articles with Prof. Schrock.

He earned a Ph.D. with Honors in Chemistry from Boston College under Prof. W. Armstrong where his graduate work focused on the synthesis and reactivity of low valent vanadium compounds. This research required mastery of both inert-atmosphere synthetic techniques and physical methods of characterization including single crystal chemical crystallography and electron paramagnetic resonance.

Prof. Bonitatibus earned a B.S. in Chemistry from Fairfield University and under a Pfizer Fellowship Award conducted research in the area of high valent manganese-oxo cluster synthesis and oxidation chemistry with Prof. J. Sarneski in collaboration with Prof. R. Crabtree at Yale.

He has a passionate interest in exploratory materials research for applications in diverse technologies enabled by liquid-phase synthesis of inorganic nanoparticles and the design, synthesis, and characterization of novel organometallics, inorganic compounds, organosilanes, and hydrosilation catalysts.

Prof. Bonitatibus has served as a reviewer for the Department of Energy, Journal of the American Chemical Society, Journal of Orthopaedic Research, ACS Nano, Journal of Biomedical Materials Research: Part B - Applied Biomaterials, Journal of Coordination Chemistry, and Congress of the World Molecular Imaging Society, as well as a referee for the Royal Society of Chemistry. He teaches Inorganic Chemistry II (CHEM 4010) at RPI twice per academic year.

Education & Training

Postdoctoral Research with Prof. R. Schrock (Nobel Laureate, 2005), Massachusetts Institute of Technology, 2001
Ph.D. with Honors in Chemistry, Boston College, 1999
B.S. in Chemistry, Fairfield University, 1993


Agency: NIH SBIR (R43/R44) Project HL152877-01, Title: Vascular CT Contrast Agent Development, Dates: 8/1/2020-7/31/2023.

Agency: NSF Major Research Instrumentation (MRI), Title: MRI: Acquisition of a Single Crystal X-ray Diffractometer for Research, Education,
and Regional Use, Dates: 2021-2022.

Agency: Momentive Performance Materials, Industrially-Sponsored Research Agreement, Title: Design of Photo-initiated Hydrosilation Catalysts for the Release Coatings Industry, Dates: 2021-2022.

Agency: NIH STTR (R42) Contract 2R42DK104580-02A1, Title: Augmenting Dual Energy CT for Novel Contrast Agents, Dates: 8/1/2019-1/31/2021.

Agency: NIH R01-EB015476, Title: Nanoparticle CT Contrast Agents for Reduced Radiation Dose and New Imaging Applications, Dates: 2013-2017.

Primary Research Focus
Inorganic and Nanoparticle Chemistry
Other Focus Areas

Nanoparticle-based diagnostic imaging agents for computed tomography
Organometallic catalysis, specifically hydrosilation
Metals in Medicine


46 Publications and 15 Issued Patents may be found in Google Scholar:

Total number of times cited: 3,967

H-index: 27

i10-index: 46

The following is a selection of recent publications in Scopus. Peter J. Bonitatibus has 44 indexed publications in the subjects of Chemistry, Materials Science, Medicine.

Philip Charles, Mallory E. Gaspard, Santiago Alvarez, Micah S. Ziegler, Amgalanbaatar Baldansuren, William H. Armstrong, K. V. Lakshmi, Peter J. Bonitatibus
Dalton Transactions
, 51
, 2022
, pp.12031-12036
Dan Xiao, Jennifer Gregg, K. V. Lakshmi, Peter J. Bonitatibus
, 11
, 2021
Jack W. Lambert, Yuxin Sun, Carol Stillson, Zhixi Li, Rahi Kumar, Sizhe Wang, Paul F. FitzGerald, Peter J. Bonitatibus, Robert E. Colborn, Jeannette C. Roberts, Peter M. Edic, Michael Marino, Benjamin M. Yeh
, 289
, 2018
, pp.103-110
Paul F. FitzGerald, Robert E. Colborn, Peter M. Edic, Jack W. Lambert, Peter J. Bonitatibus, Benjamin M. Yeh
Medical Physics
, 44
, 2017
, pp.6251-6260
Benjamin M. Yeh, Paul F. FitzGerald, Peter M. Edic, Jack W. Lambert, Robert E. Colborn, Michael E. Marino, Paul M. Evans, Jeannette C. Roberts, Zhen J. Wang, Margaret J. Wong, Peter J. Bonitatibus
Advanced Drug Delivery Reviews
, 113
, 2017
, pp.201-222
Jack W. Lambert, Paul F. FitzGerald, Peter M. Edic, Yuxin Sun, Peter J. Bonitatibus, Robert E. Colborn, Benjamin M. Yeh
Journal of Computer Assisted Tomography
, 41
, 2017
, pp.505-510
Paul F. Fitzgerald, Matthew D. Butts, Jeannette C. Roberts, Robert E. Colborn, Andrew S. Torres, Brian D. Lee, Benjamin M. Yeh, Peter J. Bonitatibus
Investigative Radiology
, 51
, 2016
, pp.786-796
Janell M. Crowder, Noel Bates, Jeannette Roberts, Andrew S. Torres, Peter J. Bonitatibus
Journal of Analytical Atomic Spectrometry
, 31
, 2016
, pp.1311-1317

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