Ryan Gilbert

Biomedical Engineering
Professor

About

Ryan Gilbert received an undergraduate degree from the University of Michigan – Ann Arbor in Chemical Engineering (High Honors) in 1997. He then received a Ph.D. degree in 2006 in Biomedical Engineering from Case Western Reserve University for his contributions in discovering specific chondroitin sulfate glycosaminoglycans responsible for inhibiting axonal regeneration. Currently, Dr. Gilbert’s laboratory is focused on developing biomaterials for cancer and central nervous system applications.

Education & Training

Ph.D., Case Western Reserve University, 2006

Publications
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The following is a selection of recent publications in Scopus. Ryan Gilbert has 97 indexed publications in the subjects of Engineering, Medicine, Materials Science.

Poly(curcumin-co-poly(ethylene glycol)) films provide neuroprotection following reactive oxygen species insult in vitro
Adelle E. Hamilton, Nikita Waskiewicz, Geraldine B. Quinones, Jeffrey R. Capadona, Marvin Bentley, Edmund F. Palermo, Ryan J. Gilbert
Journal of Neural Engineering
, 22
, 2025
.
Modular molecular design of polymerized pro-estrogen materials enables controlled astrocyte response
Devan L. Puhl, Alexis Ziemba, Samuel A.T. Ellman, Alex Hsu, Jayant Saksena, Penelope Phillips Falcone, Bailey Balouch, Deniz Rende, Tanner Fink, R. Helen Zha, Ryan J. Gilbert, Edmund F. Palermo
Journal of Materials Chemistry B
, 2025
.
Engineering elastin-like polypeptides for polyphenol capture and permeation through an in vitro nasal mucosa barrier
Derek W. Nelson, Gianna M. Scire, Conrad H. Cheung, Vrushali Varude, Geraldine Quinones, Marvin Bentley, R. Helen Zha, Ryan J. Gilbert
Journal of Drug Delivery Science and Technology
, 111
, 2025
.
Pharmacology of boldine: summary of the field and update on recent advances
Juan C. Sáez, Justin C. Burrell, Catherine M. Cahill, D. Kacy Cullen, Lakshmi A. Devi, Ryan J. Gilbert, Zachary A. Graham, Vadim J. Gurvich, Leif A. Havton, Ravi Iyengar, Rajesh Khanna, Edmund F. Palermo, Mustafa Siddiq, Carlos A. Toro, Walter Vasquez, Wei Zhao, Christopher P. Cardozo
Frontiers in Pharmacology
, 15
, 2024
.
One-Pot Assembly of Drug-Eluting Silk Coatings with Applications for Nerve Regeneration
Tanner D. Fink, Jessica L. Funnell, Ryan J. Gilbert, R. Helen Zha
ACS Biomaterials Science and Engineering
, 10
, 2024
, pp.482-496
.
Delivery of TGFβ3 from Magnetically Responsive Coaxial Fibers Reduces Spinal Cord Astrocyte Reactivity In Vitro
Jessica L. Funnell, Jasper Fougere, Diana Zahn, Silvio Dutz, Ryan J. Gilbert
Advanced Biology
, 8
, 2024
.
Delayed administration of interleukin-4 coacervate alleviates the neurotoxic phenotype of astrocytes and promotes functional recovery after a contusion spinal cord injury
Manoj K. Gottipati, Anthony R. D’Amato, Jayant Saksena, Phillip G. Popovich, Yadong Wang, Ryan J. Gilbert
Journal of Neural Engineering
, 21
, 2024
.
In Vitro Assessment of Protamine Toxicity with Neural Cells, Its Therapeutic Potential to Counter Chondroitin Sulfate Mediated Neuron Inhibition, and Its Effects on Reactive Astrocytes
Derek W. Nelson, Jessica L. Funnell, Conrad H. Cheung, Geraldine B. Quinones, Christina S. Mendoza, Marvin Bentley, Ryan J. Gilbert
Advanced Therapeutics
, 7
, 2024
.
Development of a Slow-Degrading Polymerized Curcumin Coating for Intracortical Microelectrodes
Alexis M. Ziemba, Mary Clare Crochiere Woodson, Jessica L. Funnell, Douglas Wich, Bailey Balouch, Deniz Rende, Dahlia N. Amato, Jonathan Bao, Ingrid Oprea, Dominica Cao, Neda Bajalo, Evon S. Ereifej, Jeffrey R. Capadona, Edmund F. Palermo, Ryan J. Gilbert
ACS Applied Bio Materials
, 6
, 2023
, pp.806-818
.
Curcumin Release from Biomaterials for Enhanced Tissue Regeneration Following Injury or Disease
Adelle E. Hamilton, Ryan J. Gilbert
Bioengineering
, 10
, 2023
.

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