Constellation Chair, Biological Sciences
Dr. Royer obtained her Bachelors (Licence) degree in 1979 at the University of Pierre and Marie Curie - Paris 6 in Biochemistry and Chemistry. She obtained her Ph.D. in 1985 in the Department of Biochemistry in the School of Chemical Sciences at the University of Illinois at Urbana-Champaign under the direction of Professor Gregorio Weber. She carried out postdoctoral studies at the University of Paris 7, the CNRS at Gif-sur-Yvette and at LURE under the direction of Bernard Alpert, Guy Hervé and Jean-Claude Brochon. She then took a position as User Coordinator and Research Physicist at the Laboratory for Fluorescence Dynamics in the Department of Physics at the University of Illinois - Urbana Champaign. In 1990 she moved to an Assistant Professorship in the School of Pharmacy at the University of Wisconsin-Madison, where she was promoted to Associate Professor with tenure in 1995. In 1997 she took the position of INSERM Director of Research in the Center for Structural Biochemistry in Montpellier France where, in 2002, she became Associate Director of the institute and in 2007, Director. In 2013 She moved to Rensselaer Polytechnic Institute as a Professor of Biological Sciences and chaired Constellation Professor in Bioinformatics and Biocomputation.
Ph.D. University of Illinois at Urbana-Champaigne (Biochemistry)
Bachelors (Licence) degree University of Pierre and Marie Curie Paris 6 (Biochemistry and Chemistry)
- pressure effects on biomolecules
- protein folding
- protein interaction networks
- live cell quantitative fluorescence imaging
- transcription regulation
- Zhang, Y., Berghaus, M., Klein, S., Jenkins, K., Zhang, S., McCallum, S. A., Morgan, J. E., Winter, R., Barrick, D. & Royer, C. A. High Pressure NMR and SAXS Reveals How Capping Modulates Folding Cooperativity of the pp32 Leucine Rich Repeat Protein, J. Mol. Biol. In press (2018).
- Kitazawa, S., Fossat, M.J., McCallum, S.A., Garcia, A.E and Royer, C.A. NMR and Computation Reveal a Pressure-Sensitive Folded Conformation of Trp-Cage, J. Phys. Chem B., 121, 1258-1267 (2017).
- Bourges, A., Torres Montaguth, O.E., Ghosh, A., Tadesse, W.M., Declerck, N., Aertsen, A. and Royer, C.A. High pressure activation of the Mrr restriction endonuclease in Escherichia coli involves tetramer dissociation, Nuc. Acids. Res. 45, 5232-5332 (2017).
- Gao, M., Harish, B., Berghaus, M., Seymen, R., Arns, L., McCallum, S., Royer, C. & Winter, R. Temperature and pressure limits of guanosine monophosphate self-assemblies, Scientific Rep. 7 (2017).
- Zhang, Y., Kitazawa, S., Peran, I., Stenzoski, N., McCallum, S.A., Raleigh, D.P & Royer, C.A., High Pressure ZZ-Exchange NMR Reveals Key Features of Protein Folding Transition States, J. Am. Chem. Soc., 13, 15260–15266 (2016).
- Fossat, M. J., Dao, T. P., Jenkins, K., Dellarole, M., Yang, Y., McCallum, S. A., Garcia, A. E., Barrick, D., Roumestand, C. and Royer, C. A. High-Resolution Mapping of a Repeat Protein Folding Free Energy Landscape, Biophys. J. 111, 2368-2376 (2016).
- Dellarole, M., Caro, J.A., Roche, J., Fossat, M., Barthe, P., Garcia-Moreno E., B. Royer, C.A. and Roumestand, C. Evolutionarily conserved pattern of interactions in a protein revealed by local thermal expansion properties, J. Am. Chem. Soc., (in press) 2015.
- Moutin, E., Compan, V., Raynaud, F., Clerté, C., Bouquier, N., Labesse, G., Ferguson, M.,L., Fagni, L., Royer, C.A. , Perroy, J. , Stoichiometry of scaffold complexes in living neurons - DLC2 as a dimerization engine for GKAP, J. Cell Sci. 127, 3451-3462 (2014).