Chunyu Wang

Biological Sciences
Professor

About

Professor Wang applies nuclear magnetic resonance (NMR) spectroscopy to study Alzheimer's disease and Hedgehog signaling pathway. 

Other affililations: Chemistry and Chemical Biology

Research

Other Focus Areas

Alzheimer's disease: amyloid production, aggregation and interaction, Hedgehog autopocessing: mechanism and relevance to cancer, drug discovery in Alzheimer's and cancer, NMR spectroscopy, inteins: structure and mechanism

Publications

The following is a selection of recent publications in Scopus. Chunyu Wang has 103 indexed publications in the subjects of Biochemistry, Genetics and Molecular Biology, Chemistry, and Materials Science.

Fucoidans inhibited tau interaction and cellular uptake
Weihua Jin, Chenghui Lu, Yanan Zhu, Jing Zhao, Wenjing Zhang, Lianchun Wang, Robert J. Linhardt, Chunyu Wang, Fuming Zhang
Carbohydrate Polymers
, 299
, 2023
.
Heparan Sulfate Proteoglycans in Tauopathy
Yanan Zhu, Lauren Gandy, Fuming Zhang, Jian Liu, Chunyu Wang, Laura J. Blair, Robert J. Linhardt, Lianchun Wang
Biomolecules
, 12
, 2022
.
(-)-Epigallocatechin-3-gallate Directly Binds Cyclophilin D: A Potential Mechanism for Mitochondrial Protection
Annan Wu, Jie Zhang, Quanhong Li, Xiaojun Liao, Chunyu Wang, Jing Zhao
Molecules
, 27
, 2022
.
Molecular determinants of the interaction between HSV-1 glycoprotein D and heparan sulfate
Lauren A. Gandy, Ashley J. Canning, Huan Lou, Ke Xia, Peng He, Guowei Su, Tina Cairns, Jian Liu, Fuming Zhang, Robert J. Linhardt, Gary Cohen, Chunyu Wang
Frontiers in Molecular Biosciences
, 9
, 2022
.
Proline-Rich Region II (PRR2) Plays an Important Role in Tau–Glycan Interaction: An NMR Study
Anqesha Murray, Lufeng Yan, James M. Gibson, Jian Liu, David Eliezer, Guy Lippens, Fuming Zhang, Robert J. Linhardt, Jing Zhao, Chunyu Wang
Biomolecules
, 12
, 2022
.
Cholesterol Chip for the Study of Cholesterol–Protein Interactions Using SPR
Peng He, Shannon Faris, Reddy Sudheer Sagabala, Payel Datta, Zihan Xu, Brian Callahan, Chunyu Wang, Benoit Boivin, Fuming Zhang, Robert J. Linhardt
Biosensors
, 12
, 2022
.
Covalent fragment inhibits intramembrane proteolysis
Angela Eden, Jing Zhao, Yuanyuan Xiao, James Gibson, Chunyu Wang
Frontiers in Molecular Biosciences
, 9
, 2022
.
Drug delivery of memantine with carbon dots for Alzheimer's disease: blood–brain barrier penetration and inhibition of tau aggregation
Wei Zhang, Nabin Kandel, Yiqun Zhou, Nathan Smith, Braulio C.L.B. Ferreira, Miranda Perez, Matteo L. Claure, Keenan J. Mintz, Chunyu Wang, Roger M. Leblanc
Journal of Colloid and Interface Science
, 617
, 2022
, pp.20-31
.
Structure-activity relationship of carbon nitride dots in inhibiting Tau aggregation
Yiqun Zhou, Nabin Kandel, Mattia Bartoli, Leonardo F. Serafim, Ahmed E. ElMetwally, Sophia M. Falkenberg, Xavier E. Paredes, Christopher J. Nelson, Nathan Smith, Elisa Padovano, Wei Zhang, Keenan J. Mintz, Braulio C.L.B. Ferreira, Emel Kirbas Cilingir, Jiuyan Chen, Sujit K. Shah, Rajeev Prabhakar, Alberto Tagliaferro, Chunyu Wang, Roger M. Leblanc
Carbon
, 193
, 2022
, pp.1-16
.
Nanomolar, Noncovalent Antagonism of Hedgehog Cholesterolysis: Exception to the "irreversibility Rule" for Protein Autoprocessing Inhibition
Andrew G. Wagner, Robert T. Stagnitta, Zihan Xu, John L. Pezzullo, Nabin Kandel, José Luis Giner, Douglas F. Covey, Chunyu Wang, Brian P. Callahan
Biochemistry
, 61
, 2022
, pp.1022-1028
.

View All Scopus Publications

Back to top